Denny Hamlin NASCAR Cup Series results at Fontana
| Year | Race # | Start | Finish | Car # | Sponsor | Engine | Owner | Crew Chief | Qualifying Speed | Laps | X Led | Laps Led | Status | Money | Points |
| 2006 | 2 | 5 | 12 | 11 | FedEx Kinko's | Chevrolet | Gibbs | Ford | 184.919 | 251 | 0 | 0 | running | 104575 | 127 |
| 2006 | 25 | 8 | 6 | 11 | FedEx Express | Chevrolet | Gibbs | Ford | 182.454 | 250 | 2 | 29 | running | 111800 | 155 |
| 2007 | 2 | 17 | 11 | 11 | FedEx Freight | Chevrolet | Gibbs | Ford | 183.650 | 250 | 0 | 0 | running | 116800 | 130 |
| 2007 | 25 | 9 | 19 | 11 | FedEx Express | Chevrolet | Gibbs | Ford | 180.805 | 249 | 0 | 0 | running | 108600 | 106 |
| 2008 | 2 | 12 | 41 | 11 | FedEx Freight | Toyota | Gibbs | Ford | | 193 | 0 | 0 | running | 115191 | 40 |
| 2008 | 25 | 21 | 3 | 11 | FedEx Ground | Toyota | Gibbs | Ford | 177.183 | 250 | 0 | 0 | running | 178091 | 165 |
| 2009 | 2 | 23 | 6 | 11 | FedEx Freight | Toyota | Gibbs | Ford | 180.836 | 250 | 0 | 0 | running | 129025 | 150 |
| 2009 | 30 | 1 | 37 | 11 | FedEx Ground | Toyota | Gibbs | Ford | 183.870 | 195 | 4 | 21 | accident | 123050 | 57 |
| 2010 | 2 | 25 | 29 | 11 | FedEx Freight | Toyota | Gibbs | Ford | 181.301 | 248 | 1 | 6 | running | 102250 | 81 |
| 2010 | 30 | 34 | 8 | 11 | FedEx Office | Toyota | Gibbs | Ford | 181.264 | 200 | 0 | 0 | running | 108525 | 142 |
| 2011 | 5 | 2 | 39 | 11 | FedEx Office | Toyota | Gibbs | Ford | 184.270 | 105 | 1 | 15 | engine | 123880 | 6 |
| 2012 | 5 | 1 | 11 | 11 | FedEx Express | Toyota | Gibbs | Grubb | 186.403 | 129 | 2 | 2 | running | 149771 | 34 |
| 2013 | 5 | 1 | 25 | 11 | FedEx Express | Toyota | Gibbs | Grubb | 187.451 | 199 | 1 | 3 | accident | 120080 | 20 |
| 2015 | 5 | 6 | 28 | 11 | Sport Clips | Toyota | Gibbs | Rogers | 184.233 | 209 | 2 | 56 | running | 106485 | 17 |
